Check the environmental stressors that your skin is most frequently exposed to.
UV radiation from sunlight and/or tanning salon
UV radiation penetrates into the middle layer of skin (dermis). UV radiation breaks down collagen, impairs the development of new collagen, and attacks elastin.
How can PREVAGE® MD help your skin?
In a scientific study, idebenone 1% was shown to slow up the formation of sunburn cells caused by exposure to UV radiation from the sun or tanning salon.1
UV radiation penetrates into the middle layer of skin (dermis). UV radiation breaks down collagen, impairs the development of new collagen, and attacks elastin.
How can PREVAGE® MD help your skin?
In a scientific study, idebenone 1% was shown to slow up the formation of sunburn cells caused by exposure to UV radiation from the sun or tanning salon.1
Pollution
Air pollution depletes the ozone layer in the atmosphere, allowing harmful UVA/UVB rays from the sun to affect your skin's layers, impairing its ability to repair itself. Repeated exposure to UVA/UVB causes injury to the epidermis, resulting in aging skin.
How can PREVAGE® MD help your skin?
In a laboratory study, idebenone 1% demonstrated the ability to slow up the damage that exposure to UVB causes to keratinocytes, which are the cells that primarily make up the outermost layer of the skin (epidermis).1
Air pollution depletes the ozone layer in the atmosphere, allowing harmful UVA/UVB rays from the sun to affect your skin's layers, impairing its ability to repair itself. Repeated exposure to UVA/UVB causes injury to the epidermis, resulting in aging skin.
How can PREVAGE® MD help your skin?
In a laboratory study, idebenone 1% demonstrated the ability to slow up the damage that exposure to UVB causes to keratinocytes, which are the cells that primarily make up the outermost layer of the skin (epidermis).1
‘Second-hand’ cigarette smoke
Cigarette smoke has a drying effect on your skin’s surface, which causes an increase of fine lines and wrinkles around the eye area (“crow’s-feet”).
How can PREVAGE® MD help your skin?
In a recent study of 17 subjects with moderate to severe photodamage, after using idebenone 1% for only 4 weeks, 72% of patients reported a significant reduction in the appearance of fine lines and wrinkles, and 78% noted a significant reduction in roughness and dryness.2
Cigarette smoke has a drying effect on your skin’s surface, which causes an increase of fine lines and wrinkles around the eye area (“crow’s-feet”).
How can PREVAGE® MD help your skin?
In a recent study of 17 subjects with moderate to severe photodamage, after using idebenone 1% for only 4 weeks, 72% of patients reported a significant reduction in the appearance of fine lines and wrinkles, and 78% noted a significant reduction in roughness and dryness.2
Smoking
Cigarette smoking causes biochemical changes in our bodies that accelerate aging. Smoking constricts blood vessels, reducing blood flow to your skin. Reduced blood flow means less oxygen and fewer essential nutrients are delivered to your skin’s cells.
How can PREVAGE® MD help your skin?
In a recent study where 17 subjects with moderate to severe photodamage responded after using idebenone 1% for only 4 weeks, 78% of subjects reported a significant improvement in their skin’s softness and smoothness; 61% noted significant improvement in the skin’s firmness, tightness, and elasticity; and 67% saw significant improvement in their skin’s overall appearance.2
Cigarette smoking causes biochemical changes in our bodies that accelerate aging. Smoking constricts blood vessels, reducing blood flow to your skin. Reduced blood flow means less oxygen and fewer essential nutrients are delivered to your skin’s cells.
How can PREVAGE® MD help your skin?
In a recent study where 17 subjects with moderate to severe photodamage responded after using idebenone 1% for only 4 weeks, 78% of subjects reported a significant improvement in their skin’s softness and smoothness; 61% noted significant improvement in the skin’s firmness, tightness, and elasticity; and 67% saw significant improvement in their skin’s overall appearance.2
- 1. McDaniel DH, Neudecker BA, DiNardo JC, Lewis JA II, Maibach HI. Idebenone: a new antioxidant-part I. A relative assessment of oxidative stress protection capacity compared to commonly known antioxidants. J Cosm Derm. 2005;4(1):10-17.
- 2. Data on file, Allergan, Inc. DiNardo JC. Four-week clinical expert grader evaluation of PREVAGE® MD (1.0% idebenone) for the treatment of photodamage. 2005.

